Progression of Primary Acquired Melanosis With Atypia During Pregnancy

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Progression of primary acquired melanosis with atypia during pregnancy.

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Amniotic membrane transplantation in the management of conjunctival malignant melanoma and primary acquired melanosis with atypia.

AIM To evaluate the efficacy of amniotic membrane transplantation (AMT) for the management of conjunctival malignant melanoma and primary acquired melanosis (PAM) with atypia. METHODS Four consecutive patients with histologically proved invasive, primary conjunctival malignant melanoma were treated with wide surgical excision and AMT. Amniotic membrane grafts were harvested and processed unde...

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Resolution of Primary Acquired Melanosis with Atypia after Treatment with Topical Mitomycin C and Interferon Alfa-2b

PURPOSE To report a case of primary acquired melanosis (PAM) successfully treated with combined topical mitomycin C and interferon-α2b. CASE REPORT A 75-year-old man presented with an extensive unilateral pigmented lesion involving 360° of the bulbar conjunctiva, extending to the fornices and palpebral conjunctiva. Map biopsy confirmed PAM with local atypia. Treatment was initiated with mitom...

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SCIENTIFIC CORRESPONDENCE Amniotic membrane transplantation in the management of conjunctival malignant melanoma and primary acquired melanosis with atypia

Aim—To evaluate the eYcacy of amniotic membrane transplantation (AMT) for the management of conjunctival malignant melanoma and primary acquired melanosis (PAM) with atypia. Methods—Four consecutive patients with histologically proved invasive, primary conjunctival malignant melanoma were treated with wide surgical excision and AMT. Amniotic membrane grafts were harvested and processed under st...

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Topical mitomycin chemotherapy for conjunctival malignant melanoma and primary acquired melanosis with atypia: clinical experience with histopathologic observations.

OBJECTIVES To clinically evaluate topical mitomycin chemotherapy in patients with diffuse, multifocal, or recurrent primary acquired melanosis with atypia and/or conjunctival malignant melanoma and to histopathologically study ocular tissue samples obtained before and after treatment. METHODS Chemotherapy with topical mitomycin, 0.04% 4 times daily, was administered for 28 days as the primary...

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ژورنال

عنوان ژورنال: Archives of Ophthalmology

سال: 2012

ISSN: 0003-9950

DOI: 10.1001/archophthalmol.2012.422